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Allele : Mapk12<tm2.1Cnd> mitogen-activated protein kinase 12; targeted mutation 2.1, Ana Cuenda
Primary Identifier  MGI:7615245 Allele Type  Targeted
Gene  Mapk12 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Aspartic acid codon 171 (GAC) in exon 7 was changed to alanine (GCC) (p.D171A) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 7. The neo cassette was removed through subsequent Cre-mediated recombination. The mutation renders the encoded peptide catalytically inactive.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Mapk12<D171A>,
  • Mapk12<D171A>,
  • p38gamma<171A>,
  • p38gamma<171A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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