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Allele : Pla2g6<tm1.1Otsu> phospholipase A2, group VI; targeted mutation 1.1, Kinya Otsu

Primary Identifier	MGI:7750885	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Pla2g6
Transmission	Germline	Strain of Origin	(129 x C57BL/6J)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site and FRT-flanked neo cassette was inserted upstream of exon 10 and a loxP site was inserted downstream of exon 10 via homologous recombination. Flp mediated recombination removed the neo cassette

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Pla2g6<flox>,
Pla2g6<flox>

earliestPublication:
Sugihara R, et al. (2023) Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 34. Nat Commun 14(1):4494

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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