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Allele : Mrc1<em1(cre/ERT2)Jkpns> mannose receptor, C type 1; endonuclease-mediated mutation 1, Jonathan Kipnis

Primary Identifier  MGI:7859686 Allele Type  Endonuclease-mediated
Attribute String  Inducible, Recombinase Gene  Mrc1
Strain of Origin  C57BL/6J Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  Using CRISPR/Cas9 endonuclease-mediated genome editing, a guide RNA (AGAAGCCTCATGGCCCAGAGTGG) was used to introduce a cre/ERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain) fused to a P2A self-cleaving peptide between the 5' UTR and exon 1 of the mannose receptor, C type 1 (Mrc1) gene on chromosome 2.
  • mutations:
  • Insertion
  • synonyms:
  • Mrc1<creERT2>,
  • Mrc1<creERT2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

3 Publication categories