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Search results 1101 to 1200 out of 1250 for Nfkb1

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Type Details Score
Publication
20805985 | J:164021
First Author: Bremer J
Year: 2010
Journal: PLoS One
Title: Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination.
Volume: 5
Issue: 8
Pages: e12450
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Publication
30037996 | J:264370
First Author: Sima J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.
Volume: 115
Issue: 32
Pages: 8173-8178
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Publication
36414704 | J:331419
First Author: Labbé P
Year: 2022
Journal: Commun Biol
Title: Angiopoietin-like 2 is essential to aortic valve development in mice.
Volume: 5
Issue: 1
Pages: 1277
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Publication
11707574 | J:72978
First Author: Farmer MA
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.
Volume: 98
Issue: 24
Pages: 13820-5
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Publication
25523391 | J:219824
First Author: Hendley AM
Year: 2015
Journal: Dev Biol
Title: p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.
Volume: 399
Issue: 1
Pages: 41-53
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Publication
8211130 | J:14384
First Author: Copeland NG
Year: 1993
Journal: Science
Title: A genetic linkage map of the mouse: current applications and future prospects.
Volume: 262
Issue: 5130
Pages: 57-66
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Publication
8138038 | J:17723
First Author: Kohchi C
Year: 1994
Journal: Int J Biochem
Title: Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.
Volume: 26
Issue: 1
Pages: 111-9
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Publication
22421546 | J:185743
First Author: Cotney J
Year: 2012
Journal: Genome Res
Title: Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb.
Volume: 22
Issue: 6
Pages: 1069-80
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Publication
30578393 | J:296772
 
First Author: Yin W
Year: 2019
Journal: Eur Respir J
Title: Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis.
Volume: 53
Issue: 3
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Publication
24652767 | J:213427
First Author: Adissu HA
Year: 2014
Journal: Dis Model Mech
Title: Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Volume: 7
Issue: 5
Pages: 515-24
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Publication
23123965 | J:192269
First Author: Mukhopadhyay A
Year: 2013
Journal: Dev Biol
Title: Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development.
Volume: 373
Issue: 2
Pages: 373-82
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Publication
16452166 | J:106064
First Author: Kobielak A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin.
Volume: 103
Issue: 7
Pages: 2322-7
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Publication
19500387 | J:152818
 
First Author: Melnick M
Year: 2009
Journal: BMC Dev Biol
Title: Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm.
Volume: 9
Pages: 32
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Publication
31323030 | J:279716
First Author: Braitsch CM
Year: 2019
Journal: PLoS Biol
Title: LATS1/2 suppress NFÎşB and aberrant EMT initiation to permit pancreatic progenitor differentiation.
Volume: 17
Issue: 7
Pages: e3000382
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Publication
35493520 | J:324243
 
First Author: Lei Z
Year: 2022
Journal: Front Immunol
Title: EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.
Volume: 13
Pages: 843378
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Publication
20211142 | J:160776
First Author: Ravasi T
Year: 2010
Journal: Cell
Title: An atlas of combinatorial transcriptional regulation in mouse and man.
Volume: 140
Issue: 5
Pages: 744-52
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:165965
     
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Nfkb1<em1Smoc> | MGI:7291300
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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DO Term
DOID:0081154 | common variable immunodeficiency 12
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Allele
Nod1<tm1Inoh> | MGI:2674231
Name: nucleotide-binding oligomerization domain containing 1; targeted mutation 1, Naohiro Inohara
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
15169888 | -
First Author: Lang V
Year: 2004
Journal: Mol Cell Biol
Title: ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability.
Volume: 24
Issue: 12
Pages: 5235-48
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Publication
15670770 | -
First Author: Chan H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: TRAF-dependent association of protein kinase Tpl2/COT1 (MAP3K8) with CD40.
Volume: 328
Issue: 1
Pages: 198-205
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Protein Domain
IPR017424 | MAPKKK8
Type: Family
Description: This entry represents mitogen-activated protein kinase kinase kinase 8 (MAP3K8 or COT or TPL2) (), which plays a role in the cell cycle. MAP3K8 is required for TLR4 activation of the MEK/ERK pathway. MAP3K8 is able to activate NF-kappa-B 1 (NFKB1) by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105 []. MAP3K8 forms a ternary complex with NFKB1 and TNIP2 []. MAP3K8 is recruited to the CD40 complex via a mechanism dependent on TRAF-binding sites in CD40 [].
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Strain
MGI:6159266 | B6.129P2-Nod1<tm1Inoh>/MakJ
Attribute String: mutant strain, targeted mutation, congenic
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Publication
12796777 | J:85240
First Author: Chamaillard M
Year: 2003
Journal: Nat Immunol
Title: An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.
Volume: 4
Issue: 7
Pages: 702-7
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Publication
25157574 | J:221079
First Author: Nakajima A
Year: 2014
Journal: PLoS One
Title: Commensal bacteria regulate thymic Aire expression.
Volume: 9
Issue: 8
Pages: e105904
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Publication
32704052 | J:294747
First Author: González-Ramos S
Year: 2020
Journal: Sci Rep
Title: NOD1 deficiency promotes an imbalance of thyroid hormones and microbiota homeostasis in mice fed high fat diet.
Volume: 10
Issue: 1
Pages: 12317
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Publication
16260731 | J:103431
First Author: Netea MG
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
Volume: 102
Issue: 45
Pages: 16309-14
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Publication
27479869 | J:246957
First Author: Chaves de Souza JA
Year: 2016
Journal: Immunology
Title: NOD1 in the modulation of host-microbe interactions and inflammatory bone resorption in the periodontal disease model.
Volume: 149
Issue: 4
Pages: 374-385
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Publication
16418393 | J:118808
First Author: Masumoto J
Year: 2006
Journal: J Exp Med
Title: Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo.
Volume: 203
Issue: 1
Pages: 203-13
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Publication
25824149 | J:251253
First Author: Delgado C
Year: 2015
Journal: Cardiovasc Res
Title: NOD1, a new player in cardiac function and calcium handling.
Volume: 106
Issue: 3
Pages: 375-86
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Allele
Nfkb1<M5Btlr> | MGI:6283996
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; mutation 5, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6283997 | C57BL/6J-Nfkb1<M5Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Nod1/Nod1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nfkb1/Nfkb1
Background: C57BL/6J-Nfkb1
Zygosity: hm
Has Mutant Allele: true
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Publication
31474163 | J:290464
First Author: Lee J
Year: 2019
Journal: Innate Immun
Title: NOD1/NOD2-mediated recognition of non-typeable Haemophilus influenzae activates innate immunity during otitis media.
Volume: 25
Issue: 8
Pages: 503-512
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Publication
19074871 | J:142241
First Author: Chen GY
Year: 2008
Journal: Cancer Res
Title: The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis.
Volume: 68
Issue: 24
Pages: 10060-7
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Publication
21411735 | J:172515
First Author: Hasegawa M
Year: 2011
Journal: J Immunol
Title: Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen.
Volume: 186
Issue: 8
Pages: 4872-80
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Publication
20008287 | J:159410
First Author: Asano J
Year: 2010
Journal: J Immunol
Title: Nucleotide oligomerization binding domain-like receptor signaling enhances dendritic cell-mediated cross-priming in vivo.
Volume: 184
Issue: 2
Pages: 736-45
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Publication
17579072 | J:149411
First Author: Park JH
Year: 2007
Journal: J Immunol
Title: Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells.
Volume: 179
Issue: 1
Pages: 514-21
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Publication
20308305 | J:159862
First Author: Iyer JK
Year: 2010
Journal: Infect Immun
Title: Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking.
Volume: 78
Issue: 6
Pages: 2418-28
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Publication
21108472 | J:174576
First Author: Berrington WR
Year: 2010
Journal: Eur J Immunol
Title: NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila.
Volume: 40
Issue: 12
Pages: 3519-27
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Genotype
Genotype
Symbol: Nod1/Nod1 Nod2/Nod2
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
16648853 | J:112670
First Author: Miao EA
Year: 2006
Journal: Nat Immunol
Title: Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf.
Volume: 7
Issue: 6
Pages: 569-75
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Publication
30496704 | J:287997
First Author: González-Ramos S
Year: 2019
Journal: FASEB J
Title: Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1.
Volume: 33
Issue: 3
Pages: 3912-3921
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Publication
18261938 | J:132126
First Author: Kim YG
Year: 2008
Journal: Immunity
Title: The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands.
Volume: 28
Issue: 2
Pages: 246-57
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Publication
23684310 | J:320782
First Author: Jiao Y
Year: 2013
Journal: Cell Host Microbe
Title: Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity.
Volume: 13
Issue: 5
Pages: 595-601
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Publication
35247718 | J:323351
 
First Author: Fernández-García V
Year: 2022
Journal: Biomed Pharmacother
Title: NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions.
Volume: 148
Pages: 112769
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Publication
35789437 | J:334605
First Author: Fernández-García V
Year: 2022
Journal: Cell Mol Life Sci
Title: High-fat diet activates splenic NOD1 and enhances neutrophil recruitment and neutrophil extracellular traps release in the spleen of ApoE-deficient mice.
Volume: 79
Issue: 8
Pages: 396
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Publication
32927803 | J:325363
 
First Author: González-Ramos S
Year: 2020
Journal: Cells
Title: Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis †.
Volume: 9
Issue: 9
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Publication
19620350 | J:153262
First Author: Loving CL
Year: 2009
Journal: Infect Immun
Title: Nod1/Nod2-mediated recognition plays a critical role in induction of adaptive immunity to anthrax after aerosol exposure.
Volume: 77
Issue: 10
Pages: 4529-37
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HT Experiment
E-GEOD-23497 | Identification of genes that elicit disuse muscle atrophy via the transcription factors p50 and Bcl-3
Series Id: GSE23497
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
25769919 | J:308371
First Author: Li SK
Year: 2015
Journal: J Immunol
Title: Identification of a negative regulatory role for spi-C in the murine B cell lineage.
Volume: 194
Issue: 8
Pages: 3798-807
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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