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Search results 1301 to 1400 out of 1658 for Arpp21

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Type Details Score
Publication
19286451 | J:152589
First Author: Zhang X
Year: 2009
Journal: Neuroscience
Title: Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice.
Volume: 161
Issue: 1
Pages: 53-8
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Publication
25662507 | J:221910
 
First Author: Guo HB
Year: 2015
Journal: Neuroscience
Title: Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation.
Volume: 290
Pages: 530-42
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Publication
17115048 | J:117739
First Author: Ni Y
Year: 2006
Journal: Nat Med
Title: Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation.
Volume: 12
Issue: 12
Pages: 1390-6
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Publication
28779977 | J:268116
 
First Author: Meng Y
Year: 2017
Journal: Brain Res
Title: An Aβ3-10-KLH vaccine reduced Alzheimer's disease-like pathology and had a sustained effect in Tg-APPswe/PSEN1dE9 mice.
Volume: 1673
Pages: 72-77
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Publication
27114526 | J:232198
First Author: Bettayeb K
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Relevance of the COPI complex for Alzheimer's disease progression in vivo.
Volume: 113
Issue: 19
Pages: 5418-23
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Publication
31915375 | J:293270
First Author: Gate D
Year: 2020
Journal: Nature
Title: Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.
Volume: 577
Issue: 7790
Pages: 399-404
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Publication
26199414 | J:226047
First Author: Zhang X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease.
Volume: 112
Issue: 31
Pages: 9734-9
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Publication
27581687 | J:238229
 
First Author: Yang YJ
Year: 2016
Journal: Neuroscience
Title: GluN2B-containing NMDA receptors contribute to the beneficial effects of hydrogen sulfide on cognitive and synaptic plasticity deficits in APP/PS1 transgenic mice.
Volume: 335
Pages: 170-83
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Publication
28970251 | J:270457
First Author: Cui GH
Year: 2018
Journal: FASEB J
Title: Exosomes derived from hypoxia-preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating inflammatory responses in APP/PS1 mice.
Volume: 32
Issue: 2
Pages: 654-668
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Publication
28319837 | J:243848
 
First Author: Krivinko JM
Year: 2017
Journal: Neurobiol Aging
Title: Kalirin reduction rescues psychosis-associated behavioral deficits in APPswe/PSEN1dE9 transgenic mice.
Volume: 54
Pages: 59-70
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Publication
23185565 | J:195580
First Author: Su D
Year: 2012
Journal: PLoS One
Title: Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice.
Volume: 7
Issue: 11
Pages: e50172
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Publication
25887956 | J:323141
 
First Author: Liao F
Year: 2015
Journal: Mol Neurodegener
Title: Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model.
Volume: 10
Pages: 12
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Publication
35846991 | J:342249
 
First Author: Chen CL
Year: 2022
Journal: Front Pharmacol
Title: Prominent Effects of Berbamine Hydrochloride on Alzheimer's Disease Model Mice.
Volume: 13
Pages: 939039
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Publication
16888028 | J:138349
First Author: Zamora E
Year: 2006
Journal: J Immunol
Title: Papillomavirus-like particles are an effective platform for amyloid-beta immunization in rabbits and transgenic mice.
Volume: 177
Issue: 4
Pages: 2662-2670
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Publication
21179415 | J:168997
First Author: Wang CY
Year: 2010
Journal: PLoS One
Title: Zinc overload enhances APP cleavage and Aβ deposition in the Alzheimer mouse brain.
Volume: 5
Issue: 12
Pages: e15349
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Publication
25310187 | J:261689
First Author: van Donkelaar EL
Year: 2014
Journal: PLoS One
Title: Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse.
Volume: 9
Issue: 10
Pages: e106960
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Publication
24278223 | J:209785
First Author: Ramos-Rodriguez JJ
Year: 2013
Journal: PLoS One
Title: Specific serotonergic denervation affects tau pathology and cognition without altering senile plaques deposition in APP/PS1 mice.
Volume: 8
Issue: 11
Pages: e79947
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Publication
26928013 | J:287380
 
First Author: Yan W
Year: 2016
Journal: Sci Rep
Title: NO2 inhalation promotes Alzheimer's disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication.
Volume: 6
Pages: 22429
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Publication
21969301 | J:189462
First Author: Bakalash S
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Egr1 expression is induced following glatiramer acetate immunotherapy in rodent models of glaucoma and Alzheimer's disease.
Volume: 52
Issue: 12
Pages: 9033-46
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Publication
23800542 | J:201687
 
First Author: Guo W
Year: 2013
Journal: Neurosci Lett
Title: Reduction of cerebral Aβ burden and improvement in cognitive function in Tg-APPswe/PSEN1dE9 mice following vaccination with a multivalent Aβ3-10 DNA vaccine.
Volume: 549
Pages: 109-15
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Publication
24887203 | J:217927
First Author: Pedrós I
Year: 2014
Journal: Biochim Biophys Acta
Title: Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.
Volume: 1842
Issue: 9
Pages: 1556-66
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Publication
22262260 | J:181304
First Author: Kamphuis W
Year: 2012
Journal: Glia
Title: Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model.
Volume: 60
Issue: 4
Pages: 615-29
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Publication
23133641 | J:195596
First Author: Yang SG
Year: 2012
Journal: PLoS One
Title: A peptide binding to the β-site of APP improves spatial memory and attenuates Aβ burden in Alzheimer's disease transgenic mice.
Volume: 7
Issue: 11
Pages: e48540
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Publication
30012417 | J:269104
 
First Author: Gao JY
Year: 2018
Journal: Behav Brain Res
Title: Depressive- and anxiety-like phenotypes in young adult APPSwe/PS1dE9 transgenic mice with insensitivity to chronic mild stress.
Volume: 353
Pages: 114-123
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Publication
31981651 | J:291405
 
First Author: Lian B
Year: 2020
Journal: Behav Brain Res
Title: Hippocampal overexpression of SGK1 ameliorates spatial memory, rescues Aβ pathology and actin cytoskeleton polymerization in middle-aged APP/PS1 mice.
Volume: 383
Pages: 112503
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Publication
19130883 | J:146547
First Author: Hooijmans CR
Year: 2009
Journal: Neurobiol Dis
Title: DHA and cholesterol containing diets influence Alzheimer-like pathology, cognition and cerebral vasculature in APPswe/PS1dE9 mice.
Volume: 33
Issue: 3
Pages: 482-98
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Publication
36404570 | J:344479
 
First Author: Querfurth H
Year: 2023
Journal: Behav Brain Res
Title: A PDK-1 allosteric agonist improves spatial learning and memory in a βAPP/PS-1 transgenic mouse-high fat diet intervention model of Alzheimer's disease.
Volume: 438
Pages: 114183
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Publication
37919286 | J:342269
First Author: Shoob S
Year: 2023
Journal: Nat Commun
Title: Deep brain stimulation of thalamic nucleus reuniens promotes neuronal and cognitive resilience in an Alzheimer's disease mouse model.
Volume: 14
Issue: 1
Pages: 7002
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Publication
27406855 | J:253778
 
First Author: Guo C
Year: 2016
Journal: Sci Rep
Title: Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model.
Volume: 6
Pages: 29396
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Publication
36379094 | J:344488
 
First Author: Wang X
Year: 2023
Journal: Neurobiol Aging
Title: Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway.
Volume: 121
Pages: 64-77
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Publication
26279571 | J:277592
First Author: Yang Y
Year: 2015
Journal: Cell Rep
Title: Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a.
Volume: 12
Issue: 8
Pages: 1244-51
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Publication
22922786 | J:191574
First Author: Rudinskiy N
Year: 2012
Journal: Nat Neurosci
Title: Orchestrated experience-driven Arc responses are disrupted in a mouse model of Alzheimer's disease.
Volume: 15
Issue: 10
Pages: 1422-9
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Publication
23172351 | J:285093
First Author: Kim TK
Year: 2012
Journal: Exp Mol Med
Title: Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates Aβ pathology and improves cognitive function.
Volume: 44
Issue: 12
Pages: 740-8
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Publication
24439957 | J:213885
First Author: Minogue AM
Year: 2014
Journal: Neurobiol Aging
Title: Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice.
Volume: 35
Issue: 6
Pages: 1442-52
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Publication
30849179 | J:295876
First Author: Liu SY
Year: 2019
Journal: Br J Pharmacol
Title: Protein inhibitor of activated STAT1 Ser503 phosphorylation-mediated Elk-1 SUMOylation promotes neuronal survival in APP/PS1 mice.
Volume: 176
Issue: 11
Pages: 1793-1810
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Publication
24468471 | J:213884
First Author: Liu R
Year: 2014
Journal: Neurobiol Aging
Title: Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits.
Volume: 35
Issue: 6
Pages: 1275-85
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Publication
19228947 | J:146596
First Author: Koffie RM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques.
Volume: 106
Issue: 10
Pages: 4012-7
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Publication
31078523 | J:279739
 
First Author: Xiang XJ
Year: 2019
Journal: Exp Neurol
Title: Mitochondrial methionine sulfoxide reductase B2 links oxidative stress to Alzheimer's disease-like pathology.
Volume: 318
Pages: 145-156
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Publication
32034757 | J:332688
First Author: Yu XL
Year: 2020
Journal: Br J Pharmacol
Title: Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid-β had distinct effects on neuropathology and cognitive deficits in EAE/AD mice.
Volume: 177
Issue: 12
Pages: 2860-2871
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Publication
26147692 | J:252327
First Author: Dorresteijn B
Year: 2015
Journal: FEBS J
Title: Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
Volume: 282
Issue: 18
Pages: 3618-31
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Publication
30389579 | J:270655
First Author: Yuan C
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Volume: 1865
Issue: 1
Pages: 161-180
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Publication
31849582 | J:309654
 
First Author: Guo J
Year: 2019
Journal: Front Neurosci
Title: MiR-409-5p as a Regulator of Neurite Growth Is Down Regulated in APP/PS1 Murine Model of Alzheimer's Disease.
Volume: 13
Pages: 1264
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Publication
22015609 | J:203613
First Author: Kim JY
Year: 2012
Journal: Cell Death Differ
Title: Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-β plaques.
Volume: 19
Issue: 4
Pages: 680-91
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Publication
26643273 | J:346652
First Author: Shi S
Year: 2016
Journal: Eur J Immunol
Title: Gx-50 reduces β-amyloid-induced TNF-α, IL-1β, NO, and PGE2 expression and inhibits NF-κB signaling in a mouse model of Alzheimer's disease.
Volume: 46
Issue: 3
Pages: 665-76
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Publication
29974866 | J:263868
First Author: Papadimitriou C
Year: 2018
Journal: Dev Cell
Title: 3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity.
Volume: 46
Issue: 1
Pages: 85-101.e8
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Publication
33951283 | J:346658
First Author: Souder DC
Year: 2021
Journal: Aging Cell
Title: Rhesus monkeys as a translational model for late-onset Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13374
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Publication
28750017 | J:246030
First Author: Zhang C
Year: 2017
Journal: PLoS One
Title: Corticotropin-releasing factor receptor-1 modulates biomarkers of DNA oxidation in Alzheimer's disease mice.
Volume: 12
Issue: 7
Pages: e0181367
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Publication
33651103 | J:346659
 
First Author: Rynearson KD
Year: 2021
Journal: J Exp Med
Title: Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention.
Volume: 218
Issue: 4
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Publication
22738723 | J:191600
First Author: Sierksma AS
Year: 2013
Journal: Neurobiol Aging
Title: Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice.
Volume: 34
Issue: 1
Pages: 319-37
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Publication
33441550 | J:310058
First Author: Hashimoto Y
Year: 2021
Journal: Transl Psychiatry
Title: Restoration of the reduced CLSP activity alleviates memory impairment in Alzheimer disease.
Volume: 11
Issue: 1
Pages: 44
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Publication
20847045 | J:167024
First Author: Lewis TL
Year: 2010
Journal: J Biol Chem
Title: Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease.
Volume: 285
Issue: 47
Pages: 36958-68
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Publication
36185477 | J:346675
 
First Author: Chu X
Year: 2022
Journal: Front Aging Neurosci
Title: Nicotinamide adenine dinucleotide supplementation drives gut microbiota variation in Alzheimer's mouse model.
Volume: 14
Pages: 993615
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Publication
35738259 | J:346676
First Author: Ju YH
Year: 2022
Journal: Cell Metab
Title: Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer's disease.
Volume: 34
Issue: 8
Pages: 1104-1120.e8
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Publication
22177661 | J:181369
First Author: Zhang Z
Year: 2012
Journal: Mol Immunol
Title: Possible allelic structure of IgG2a and IgG2c in mice.
Volume: 50
Issue: 3
Pages: 169-71
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Publication
27333181 | J:258449
First Author: More SS
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Early Detection of Amyloidopathy in Alzheimer's Mice by Hyperspectral Endoscopy.
Volume: 57
Issue: 7
Pages: 3231-8
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Publication
21044080 | J:167060
First Author: Perez Nievas BG
Year: 2011
Journal: J Neurochem
Title: Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice.
Volume: 116
Issue: 1
Pages: 43-52
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Publication
31417357 | J:281860
 
First Author: Myhre CL
Year: 2019
Journal: Front Cell Neurosci
Title: Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.
Volume: 13
Pages: 308
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Publication
33623128 | J:303883
First Author: Lau JKY
Year: 2021
Journal: Sci Rep
Title: Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model.
Volume: 11
Issue: 1
Pages: 4359
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Publication
21788993 | J:296870
First Author: Xiong H
Year: 2011
Journal: Neurosci Bull
Title: Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer's disease.
Volume: 27
Issue: 4
Pages: 221-32
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Publication
34919273 | J:346677
First Author: Gervais É
Year: 2022
Journal: J Comp Neurol
Title: Structural analysis of the microglia-interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease.
Volume: 530
Issue: 9
Pages: 1423-1437
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Publication
19941887 | J:243874
First Author: Harrison FE
Year: 2010
Journal: Pharmacol Biochem Behav
Title: Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice.
Volume: 94
Issue: 4
Pages: 543-52
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Publication
26264859 | J:232255
First Author: Yeh CW
Year: 2015
Journal: Neurobiol Aging
Title: Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice.
Volume: 36
Issue: 11
Pages: 2984-2994
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Publication
17549256 | J:122022
First Author: Shaftel SS
Year: 2007
Journal: J Clin Invest
Title: Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology.
Volume: 117
Issue: 6
Pages: 1595-604
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Publication
26116027 | J:228235
First Author: Akhter H
Year: 2015
Journal: Toxicol Sci
Title: Cyclic Ozone Exposure Induces Gender-Dependent Neuropathology and Memory Decline in an Animal Model of Alzheimer's Disease.
Volume: 147
Issue: 1
Pages: 222-34
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Publication
21527912 | J:173179
First Author: Kumar S
Year: 2011
Journal: EMBO J
Title: Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.
Volume: 30
Issue: 11
Pages: 2255-65
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Publication
34526539 | J:312220
First Author: Benseny-Cases N
Year: 2021
Journal: Sci Rep
Title: In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimer's disease transgenic mice using synchrotron-based infrared imaging.
Volume: 11
Issue: 1
Pages: 18368
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Publication
26227742 | J:232260
First Author: Jones RS
Year: 2015
Journal: Neurobiol Aging
Title: Inhibition of JAK2 attenuates the increase in inflammatory markers in microglia from APP/PS1 mice.
Volume: 36
Issue: 10
Pages: 2716-24
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Publication
36819109 | J:337529
 
First Author: Das S
Year: 2023
Journal: Front Cell Dev Biol
Title: Region-specific heterogeneity in neuronal nuclear morphology in young, aged and in Alzheimer's disease mouse brains.
Volume: 11
Pages: 1032504
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Publication
28835279 | J:312219
First Author: Willén K
Year: 2017
Journal: Mol Neurodegener
Title: Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.
Volume: 12
Issue: 1
Pages: 61
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Publication
33958667 | J:318046
First Author: D'Angelo C
Year: 2021
Journal: Sci Rep
Title: nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse.
Volume: 11
Issue: 1
Pages: 9711
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: B6;C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Itm2b/Itm2b<+> Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129 * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nr1h2/Nr1h2 Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129S6/SvEvTac * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nr1h3/Nr1h3 Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129S6/SvEvTac * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ptger2/Ptger2 Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129S6/SvEvTac * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rtn4rl2/Rtn4rl2 Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129S6/SvEvTac * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: CAST.Cg-Tg(APPswe,PSEN1dE9)85Dbo/How
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lepr/Lepr<+> Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: C3H * C57BL/6 * C57BLKS/J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrn/Agrn Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/? Tg(MGS1-19375/CFP)2R9Rwb/?
Background: involves: C3H * C57BL/6 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: D2.Cg-Tg(APPswe,PSEN1dE9)85Dbo
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hc<1>/Hc<1> Tg(APPswe,PSEN1dE9)85Dbo/?
Background: D2.Cg-Tg(APPswe,PSEN1dE9)85Dbo
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lrrtm3/Lrrtm3 Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6JHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: C3H/HeH * C57BL/6JNju
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPswe,PSEN1dE9)85Dbo/?
Background: WSB.Cg-Tg(APPswe,PSEN1dE9)85Dbo/How
Zygosity: ot
Has Mutant Allele: true
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Publication
27030769 | J:231748
First Author: Sakae N
Year: 2016
Journal: J Neurosci
Title: ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
Volume: 36
Issue: 13
Pages: 3848-59
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Publication
18710920 | J:138978
First Author: Song S
Year: 2008
Journal: J Cell Biol
Title: E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity.
Volume: 182
Issue: 4
Pages: 675-84
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Publication
33667711 | J:305937
 
First Author: Mitsubori M
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Identification of highest neurotoxic amyloid-β plaque type showing reduced contact with astrocytes.
Volume: 549
Pages: 67-74
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Publication
33580194 | J:309006
First Author: Takeda K
Year: 2021
Journal: Commun Biol
Title: Mitochondrial ubiquitin ligase alleviates Alzheimer's disease pathology via blocking the toxic amyloid-β oligomer generation.
Volume: 4
Issue: 1
Pages: 192
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Publication
22820466 | J:190064
First Author: Um JW
Year: 2012
Journal: Nat Neurosci
Title: Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.
Volume: 15
Issue: 9
Pages: 1227-35
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Publication
23954170 | J:211980
First Author: Ohno M
Year: 2014
Journal: Neurobiol Aging
Title: Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model.
Volume: 35
Issue: 1
Pages: 213-22
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Publication
23223301 | J:193190
First Author: Kummer MP
Year: 2012
Journal: J Neurosci
Title: Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
Volume: 32
Issue: 49
Pages: 17824-9
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Publication
17913918 | J:125592
First Author: Li T
Year: 2007
Journal: J Neurosci
Title: Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.
Volume: 27
Issue: 40
Pages: 10849-59
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Publication
31794021 | J:284850
First Author: Koronyo-Hamaoui M
Year: 2020
Journal: Brain
Title: Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease.
Volume: 143
Issue: 1
Pages: 336-358
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Publication
24760848 | J:210613
First Author: Woodling NS
Year: 2014
Journal: J Neurosci
Title: Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
Volume: 34
Issue: 17
Pages: 5882-94
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Publication
27796320 | J:271412
 
First Author: Ma Z
Year: 2016
Journal: Sci Rep
Title: Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes.
Volume: 6
Pages: 36035
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