| Primary Identifier | MGI:2180502 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Bub3 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = W9.5 (129S1/Sv-p+ Tyr+ Kitl+) or 129/1 (129P2/OlaHsd) |
| molecularNote | Exons 2 and 3 were replaced with a lacZ-neomycin fusion gene lacking a promoter but possessing a splice acceptor site and an internal ribosome entry site (IRES). The authors believed that only the first 65 amino acids would be translated, producing a protein lacking three of the four WD40 domains as well as the protein-interacting kinetochore domain. |
