| Primary Identifier | MGI:2386955 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Ifnb1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The coding region of the gene was deleted and replaced with a GFP-neo-loxP cassette via homologous recombination. The targeted mutation places the green fluorescent protein gene under the control of the endogenous promoter. RT-PCR analysis of mouse embryonic fibroblasts derived from homozygous mutant animals verified the absence of Ifnb expression and presence of GFP transcripts. |
