| Primary Identifier | MGI:2450883 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tec |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The insertion of a neomycin selection cassette disrupted the endogenous allele by replacing exon 2 and surrounding intronic sequence. The deleted exon contained the start codon, encoded 45 residues of the Pleckstrin homology domain, and is common to the 4 known isoforms. Western blot analysis showed an absence of full length and truncated protein. |
