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Allele : Igll1<tm1Shim> immunoglobulin lambda-like polypeptide 1; targeted mutation 1, Takeyuki Shimizu

Primary Identifier  MGI:2677170 Allele Type  Targeted
Attribute String  Null/knockout Gene  Igll1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 of this gene as well as the entire VpreB1 gene were replaced with a neomycin resistance gene flanked by loxP sites. mRNA transcripts of this gene were not detected by Northern blot analysis but small amounts of a truncated product containing sliced exons 2 and 3 could be detected by PCR. No protein product was predicted from this mRNA. All mRNA product could be eliminated by cre mediated excision of the neomycin insert but this had no ultimate effect on the observed phenotypes.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • lambda 5-,
  • lambda 5-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories