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Allele : Spo11<tm1Rdco> SPO11 initiator of meiotic double stranded breaks; targeted mutation 1, R Daniel Camerini-Otero

Primary Identifier  MGI:3027823 Allele Type  Targeted
Attribute String  Null/knockout Gene  Spo11
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 starting after the sequence coding for the 3rd amino acid after the second "in frame" ATG through nucleotide 35 of the first intron was replaced with a PGK-neomycin cassette in reverse orientation. This removes the splice donor site. Absence of transcript was confirmed by Northern blot analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Spo11<->,
  • Spo11<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

22 Publication categories