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Allele : Htr3a<tm1Jul> 5-hydroxytryptamine (serotonin) receptor 3A; targeted mutation 1, David Julius

Primary Identifier  MGI:3055155 Allele Type  Targeted
Attribute String  Null/knockout Gene  Htr3a
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neomycin cassette was inserted in place of exons 7 and 8, which encode the first three putative transmembrane domains of the channel protein. Northern blot and In situ autoradiography demonstrated gene ablation was successful.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Htr3a<tm1Bbm>,
  • 5-HT3R-A<->,
  • 5-HT3R-A<->,
  • Htr3a<tm1Bbm>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

32 Publication categories