Primary Identifier | MGI:3055155 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Htr3a |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-neomycin cassette was inserted in place of exons 7 and 8, which encode the first three putative transmembrane domains of the channel protein. Northern blot and In situ autoradiography demonstrated gene ablation was successful. |