Primary Identifier | MGI:3510962 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lat2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2-8 were replaced with a neomycin resistance gene. The deleted region encoded the 5' terminal from residues 1-113, including the transmembrane domain and palmitoylation site. Immunoprecipitation of protein from splenocyte and mast cell lysates followed by immunoblot confirmed the absence of protein in mutants. |