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Allele : Tnfrsf1a<tm2Gkl> tumor necrosis factor receptor superfamily, member 1a; targeted mutation 2, George Kollias

Primary Identifier	MGI:3686874	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Tnfrsf1a
Transmission	Germline	Strain of Origin	129S/SvEv-Gpi1<c>
Is Recombinase	false	Is Wild Type	false

molecularNote

A floxed neo was inserted into intron 5 of the locus to create this conditional gain-of-function allele. The presence of the neo prevents expression of the gene.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
p55TnfR<cneo>,
TnfRI<flxneo>,
TnfRI<flxneo>,
p55TnfR<cneo>

earliestPublication:
Victoratos P, et al. (2006) FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses. Immunity 24(1):65-77

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

10 Publication categories

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