| Primary Identifier | MGI:5751243 | Allele Type | Targeted |
| Gene | Cry2 | Transmission | Germline |
| Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 11 was replaced with an FRT- and loxP-flanked neomycin resistance cassette and modified exon 11 in which a point mutation (T to G) results in the amino acid substitution of alanine for serine at position 557 (S557A). Flp-mediated recombination removed the selection cassette. CRY2 protein expressed in the liver of homozygous mutant mice showed no immunoreactivity with the antibody recognizing Ser557-phosphorylated CRY2. |
